{"id":846,"date":"2016-09-23T11:25:41","date_gmt":"2016-09-23T11:25:41","guid":{"rendered":"http:\/\/tecnodiabetes.ai2.upv.es\/index.php\/solare\/?lang=en"},"modified":"2025-08-14T10:32:23","modified_gmt":"2025-08-14T08:32:23","slug":"solare","status":"publish","type":"page","link":"https:\/\/tecnodiabetes.ai2.upv.es\/index.php\/solare\/?lang=en","title":{"rendered":"Solare"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00bb1&#8243; fullwidth=\u00bbon\u00bb custom_padding_last_edited=\u00bbon|desktop\u00bb admin_label=\u00bbSecci\u00f3n\u00bb _builder_version=\u00bb4.16&#8243; background_color=\u00bb#f15d2f\u00bb custom_padding=\u00bb30px|||\u00bb custom_padding_tablet=\u00bb50px|0|50px|0&#8243; custom_padding_phone=\u00bb50px|0|50px|0&#8243; transparent_background=\u00bboff\u00bb padding_mobile=\u00bboff\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bbon\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_fullwidth_code admin_label=\u00bbC\u00f3digo de anchura completa\u00bb _builder_version=\u00bb4.16&#8243; global_colors_info=\u00bb{}\u00bb].[\/et_pb_fullwidth_code][\/et_pb_section][et_pb_section fb_built=\u00bb1&#8243; custom_padding_last_edited=\u00bbon|desktop\u00bb admin_label=\u00bbSecci\u00f3n\u00bb _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb54px|0px|0px|0px\u00bb custom_padding_tablet=\u00bb50px|0|50px|0&#8243; custom_padding_phone=\u00bb50px|0|50px|0&#8243; transparent_background=\u00bboff\u00bb padding_mobile=\u00bboff\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_row _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb column_structure=\u00bb1_5,1_5,1_5,1_5,1_5&#8243; custom_margin=\u00bb-52px||||false|false\u00bb hover_enabled=\u00bb0&#8243; sticky_enabled=\u00bb0&#8243;][et_pb_column _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb type=\u00bb1_5&#8243;][\/et_pb_column][et_pb_column _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb type=\u00bb1_5&#8243;][\/et_pb_column][et_pb_column _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb type=\u00bb1_5&#8243;][\/et_pb_column][et_pb_column _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb type=\u00bb1_5&#8243;][\/et_pb_column][et_pb_column _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb type=\u00bb1_5&#8243;][et_pb_image src=\u00bbhttps:\/\/tecnodiabetes.ai2.upv.es\/wp-content\/uploads\/2025\/08\/normal-reproduction-low-resolution.jpg\u00bb _builder_version=\u00bb4.27.4&#8243; _module_preset=\u00bbdefault\u00bb title_text=\u00bbnormal-reproduction-low-resolution\u00bb hover_enabled=\u00bb0&#8243; sticky_enabled=\u00bb0&#8243; width=\u00bb50%\u00bb][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=\u00bboff\u00bb column_padding_mobile=\u00bbon\u00bb admin_label=\u00bbrow\u00bb _builder_version=\u00bb4.27.4&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb hover_enabled=\u00bb0&#8243; make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb custom_margin=\u00bb-20px||||false|false\u00bb sticky_enabled=\u00bb0&#8243;][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; text_font=\u00bb|||on|\u00bb background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb text_orientation=\u00bbcenter\u00bb module_alignment=\u00bbcenter\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb saved_tabs=\u00bball\u00bb inline_fonts=\u00bbMontserrat\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<h4><span style=\"font-family: Montserrat; color: #999999;\">PROJECTS<\/span><\/h4>\n<h3>SOLARE<\/h3>\n<p><span style=\"font-family: Montserrat; font-size: large;\">Seeking solutions for the artificial pancreas: new methods for improving continuous<br \/>\nglucose monitoring and closed loop postprandial glycaemic control<\/span><br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb1_2,1_2&#8243; padding_mobile=\u00bboff\u00bb column_padding_mobile=\u00bbon\u00bb admin_label=\u00bbRow\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_image src=\u00bbhttps:\/\/tecnodiabetes.ai2.upv.es\/wp-content\/uploads\/2016\/11\/foto-infodiabetes.jpg\u00bb align_tablet=\u00bbcenter\u00bb align_phone=\u00bbcenter\u00bb align_last_edited=\u00bbon|desktop\u00bb admin_label=\u00bbImagen\u00bb _builder_version=\u00bb4.16&#8243; animation_style=\u00bbslide\u00bb animation_direction=\u00bbleft\u00bb animation_duration=\u00bb500ms\u00bb animation_intensity_slide=\u00bb10%\u00bb animation=\u00bbleft\u00bb sticky=\u00bboff\u00bb always_center_on_mobile=\u00bbon\u00bb global_colors_info=\u00bb{}\u00bb][\/et_pb_image][\/et_pb_column][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<h4>Administrative Data<\/h4>\n<p><strong>Project reference:<\/strong> FP7-PEOPLE-2009-IEF, ref 252085<br \/>\n<strong style=\"font-size: 14px;\">Title:<\/strong><span style=\"font-size: 14px;\"> Seeking solutions for the artificial pancreas: new methods for improving continuous glucose monitoring and closed loop postprandial glycaemic control \u2013 SOLARE<br \/>\n<\/span><strong style=\"font-size: 14px;\">Participating centers:<\/strong><span style=\"font-size: 14px;\"> Universitat Polit\u00e8cnica de Val\u00e8ncia<br \/>\n<\/span><strong style=\"font-size: 14px;\">Principal Investigator:<\/strong><span style=\"font-size: 14px;\"> Jorge Bondia (Host); Paolo Rossetti (Fellow)<br \/>\n<\/span><strong style=\"font-size: 14px;\">Funded by:<\/strong><span style=\"font-size: 14px;\"> European Community<br \/>\n<\/span><strong style=\"font-size: 14px;\">Duration:<\/strong><span style=\"font-size: 14px;\"> 01\/10\/2010-01\/10\/2012<br \/>\n<\/span><strong style=\"font-size: 14px;\">Funding awarded:<\/strong><span style=\"font-size: 14px;\"> \u20ac160,793.00<\/span><br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=\u00bboff\u00bb column_padding_mobile=\u00bbon\u00bb admin_label=\u00bbRow\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb custom_padding=\u00bb27px|0px|0px|0px\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_color=\u00bb#ffffff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<h4>Project Summary<\/h4>\n<p>Over the past two decades, technological progress has driven research into closed-loop glucose control systems, known as artificial pancreases, for the efficient treatment of type 1 diabetes. Preliminary studies using commercial insulin pumps and continuous glucose monitors (CGMs) suggest that, in controlled environments, automated insulin delivery systems can achieve better glycemic control than self-directed open-loop systems. These promising results led the Juvenile Diabetes Research Foundation (JDRF) to advance this research by launching its Artificial Pancreas project three years ago, and the U.S. Food and Drug Administration (FDA) to designate the artificial pancreas as a priority in its Critical Path Initiative. However, to date, only a few prototypes have been developed and validated in controlled hospital settings. Challenges remain, such as:     <\/p>\n<p>1. Coping with major perturbations affecting the system, such as meals and exercise;<br \/>\n2. Robustness to the high variability of patient physiological behavior;<br \/>\n3. Accuracy and reliability of continuous glucose monitors, which need to be improved;<br \/>\n4. Safety of insulin pumps and fault detection;<br \/>\n5. Adequate correction of slow controller action due to delays in the control loop.<\/p>\n<p>The overall objective of this project is to develop a safe and efficient closed-loop blood glucose monitoring system after a meal. This will be achieved through: <\/p>\n<p>1. The development of new closed-loop strategies for postprandial monitoring. A new algorithm for optimizing postprandial monitoring will be clinically validated. Clinical results will drive the development of new closed-loop strategies to adequately compensate for meals without the risk of hypoglycemia.<br \/>\n2. The improvement of the accuracy and reliability of continuous glucose monitors for detecting hypoglycemia. Continuous glucose monitors estimate plasma glucose from interstitial measurements. However, the relationship between plasma and interstitial glucose is still poorly understood, especially under dynamic conditions. This project will evaluate and model this relationship with the specific goal of developing new calibration strategies that improve the performance of continuous glucose monitors in hypoglycemia.     <\/p>\n<p>It is expected that improvements in control algorithms and measurement accuracy will allow for the performance and safety required for automatic post-ingestion monitoring.<br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row padding_mobile=\u00bboff\u00bb column_padding_mobile=\u00bbon\u00bb admin_label=\u00bbrow\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb custom_padding=\u00bb25.5px|0px|17px|0px\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<h4>Researchers<\/h4>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb1_3,1_3,1_3&#8243; padding_mobile=\u00bboff\u00bb column_padding_mobile=\u00bbon\u00bb admin_label=\u00bbrow\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb custom_padding=\u00bb0px|0px|25.5px|0px\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<h6>Universitat Polit\u00e8cnica De Val\u00e8ncia:<\/h6>\n<ul>\n<li>Jorge Bondia (host)<\/li>\n<li>Paolo Rossetti (fellow)<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n<h6>Hospital Cl\u00ednico de Valencia<\/h6>\n<ul>\n<li>F. Javier Ampudia<\/li>\n<\/ul>\n<p>&nbsp;<br \/>\n[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16&#8243; background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]&nbsp;<br \/>\n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>PROJECTS SOLARE Seeking solutions for the artificial pancreas: new methods for improving continuous glucose monitoring and closed loop postprandial glycaemic control Administrative Data Project reference: FP7-PEOPLE-2009-IEF, ref 252085 Title: Seeking solutions for the artificial pancreas: new methods for improving continuous glucose monitoring and closed loop postprandial glycaemic control \u2013 SOLARE Participating centers: Universitat Polit\u00e8cnica de [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-846","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - 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