{"id":801,"date":"2016-09-23T11:25:41","date_gmt":"2016-09-23T11:25:41","guid":{"rendered":"http:\/\/tecnodiabetes.ai2.upv.es\/?page_id=801"},"modified":"2025-08-14T10:25:57","modified_gmt":"2025-08-14T08:25:57","slug":"solare","status":"publish","type":"page","link":"https:\/\/tecnodiabetes.ai2.upv.es\/index.php\/solare\/","title":{"rendered":"Solare"},"content":{"rendered":"

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PROYECTOS<\/span><\/h4>\n

SOLARE<\/h3>\n

Seeking solutions for the artificial pancreas: new methods for improving continuous
\nglucose monitoring and closed loop postprandial glycaemic control<\/span>
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Datos administrativos<\/h4>\n

Referencia del proyecto:<\/strong> FP7-PEOPLE-2009-IEF, ref 252085
\nT\u00edtulo:<\/strong> Seeking solutions for the artificial pancreas: new methods for improving continuous\u00a0glucose monitoring and closed loop postprandial glycaemic control \u2013 SOLARE
\n<\/span>Entidades participantes:<\/strong> Universitat Polit\u00e8cnica de Val\u00e8ncia
\n<\/span>Investigador principal:<\/strong> Jorge Bondia (Host); Paolo Rossetti (Fellow)
\n<\/span>Entidad financiadora:<\/strong> Comunidad Europea
\n<\/span>Duraci\u00f3n:<\/strong> 01\/10\/2010-01\/10\/2012
\n<\/span>Financiaci\u00f3n recibida:<\/strong> 160.793,00\u20ac<\/span>
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Resumen del proyecto<\/h4>\n

En las \u00faltimas dos d\u00e9cadas, el progreso tecnol\u00f3gico ha impulsado la investigaci\u00f3n en sistemas de control de glucosa en lazo cerrado, el llamado p\u00e1ncreas artificial, para el tratamiento eficiente de la diabetes tipo 1. Estudios preliminares empleando bombas de insulina y monitores cont\u00ednuos de glucosa (CGM) comerciales, sugieren que en entornos controlados, los sistemas autom\u00e1ticos de administraci\u00f3n de insulina pueden obtener un mejor control gluc\u00e9mico que los sistemas de lazo abierto en los que el proprio sujeto toma decisiones. Estos resultados prometedores llevaron a la Juvenile Diabetes Research Foundation (JDRF) a impulsar dicha investigaci\u00f3n lanzado hace tres a\u00f1os su proyecto Artificial Pancreas, as\u00ed como a la Food and Drug Administration (FDA) en EE.UU. a designar al p\u00e1ncreas artificial como una prioridad en su Critical Path Initiative. Sin embargo, a d\u00eda de hoy s\u00f3lo se han desarrollado unos pocos prototipos, validados en entornos hospitalarios controlados. De hecho existen todav\u00eda desaf\u00edos como:<\/p>\n

1. Hacer frente a las grandes perturbaciones que afectan al sistema, como las comidas y el ejercicio;
\n2. Robustez frente a la gran variabilidad del comportamiento fisiol\u00f3gico del paciente;
\n3. Exactitud y fiabilidad de los monitores continuos de glucosa, que deben mejorarse;
\n4. Saguridad de las bombas de insulina y detecci\u00f3n de fallos;
\n5. Correcci\u00f3n adecuada de la acci\u00f3n lenta de los controladores debido a retrasos en el lazo de control.<\/p>\n

El objetivo general de este proyecto es obtener un sistema de control de glucemia en lazo cerrado seguro y eficiente tras una ingesta. Esto se alcanzar\u00e1 a trav\u00e9s de:<\/p>\n

1. El desarrollo de nuevas estrategias de lazo cerrado para el control postprandial. Se llevar\u00e1 a cabo una validaci\u00f3n cl\u00ednica de un nuevo algoritmo para la optimizaci\u00f3n del control postprandial. Los resultados cl\u00ednicos impulsar\u00e1n el desarrollo de nuevas estrategias de lazo cerrado para compensar adecuadamente las comidas sin riesgo de hipoglucemia.
\n2. La mejora de la exactitud y fiabilidad de los monitores continuos de glucosa para detectar hipoglucemia. Los monitores continuos de glucosa estiman la glucosa en plasma a partir de medidas en el intersticio. Sin embargo, la relaci\u00f3n entre la glucosa plasm\u00e1tica e intersticial no se conoce bien todav\u00eda, especialmente en condiciones din\u00e1micas. En este proyecto dicha relaci\u00f3n se evaluar\u00e1 y modelar\u00e1, con el objetivo espec\u00edfico de desarrollar nuevas estrategias de calibraci\u00f3n que mejoren las prestaciones de los monitores continuos de glucosa en hipoglucemia.<\/p>\n

Se espera que la mejora en algoritmos de control y exactitud de la medida permitir\u00e1 obtener las prestaciones y seguridad exigidas para el control autom\u00e1tico tras una ingesta.
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Investigadores<\/h4>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb1_3,1_3,1_3″ padding_mobile=\u00bboff\u00bb column_padding_mobile=\u00bbon\u00bb admin_label=\u00bbrow\u00bb _builder_version=\u00bb4.16″ background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb custom_padding=\u00bb0px|0px|25.5px|0px\u00bb make_fullwidth=\u00bboff\u00bb use_custom_width=\u00bboff\u00bb width_unit=\u00bboff\u00bb custom_width_px=\u00bb1080px\u00bb custom_width_percent=\u00bb80%\u00bb global_colors_info=\u00bb{}\u00bb][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16″ background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

Universitat Polit\u00e8cnica de Val\u00e8ncia:<\/h6>\n
    \n
  • Jorge Bondia (host)<\/li>\n
  • Paolo Rossetti (fellow)<\/li>\n<\/ul>\n

    [\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.16″ background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

    Hospital Cl\u00ednico de Valencia<\/h6>\n
      \n
    • F. Javier Ampudia<\/li>\n<\/ul>\n

       
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      \n[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"

      PROYECTOS SOLARE Seeking solutions for the artificial pancreas: new methods for improving continuous glucose monitoring and closed loop postprandial glycaemic control Datos administrativos Referencia del proyecto: FP7-PEOPLE-2009-IEF, ref 252085 T\u00edtulo: Seeking solutions for the artificial pancreas: new methods for improving continuous\u00a0glucose monitoring and closed loop postprandial glycaemic control \u2013 SOLARE Entidades participantes: Universitat Polit\u00e8cnica de […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-801","page","type-page","status-publish","hentry"],"yoast_head":"\nProyecto de p\u00e1ncreas artificial SOLARE - Tecnodiabetes<\/title>\n<meta name=\"description\" content=\"Conoce el proyecto SOLARE "Seeking solutions for the artificial pancreas: new methods for improving CGM and closed loop postprandial glycaemic control"\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tecnodiabetes.ai2.upv.es\/index.php\/solare\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Proyecto de p\u00e1ncreas artificial SOLARE - 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