{"id":2877,"date":"2023-01-20T16:39:01","date_gmt":"2023-01-20T15:39:01","guid":{"rendered":"https:\/\/tecnodiabetes.ai2.upv.es\/?page_id=2877"},"modified":"2025-06-17T13:53:17","modified_gmt":"2025-06-17T11:53:17","slug":"flex-ap","status":"publish","type":"page","link":"https:\/\/tecnodiabetes.ai2.upv.es\/index.php\/flex-ap\/?lang=en","title":{"rendered":"FLEX-AP"},"content":{"rendered":"

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PROJECTS<\/span><\/h4>\n

FLEX-AP<\/h3>\n

BEYOND HYBRID ARTIFICIAL PANCREAS SYSTEMS: RELIEVING CARB COUNTING VIA FLEXIBLE-USER-INTERACTION MULTIPLE-INPUT CONTROL ARCHITECTURES (FLEX-AP)<\/span><\/span><\/p>\n

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Administrative data<\/h4>\n

<\/strong><\/p>\n

Program:<\/strong> Subvenciones 2022 programa Prometeo para grupos de investigaci\u00f3n de excelencia.
Project reference: <\/strong>CIPROM\/2021\/012
Title:<\/strong> Beyond hybrid artificial pancreas systems: relieving carb counting via flexible-user-interaction multiple-input control architectures (FLEX-AP)
Participating centers:<\/strong> Universitat Polit\u00e8cnica de Val\u00e8ncia
Principal investigator:<\/strong> Jorge Bondia
Funded by:<\/strong> Generalitat Valenciana, Conselleria d’Educaci\u00f3, Cultura, Universitats i Ocupaci\u00f3
Duration:<\/strong> 01\/01\/2022- 31\/12\/2025
Funding awarded:<\/strong> \u20ac564,140.54<\/p>\n

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Summary of the project<\/h4>\n

There is a need to leverage improvement of glycemic control and user experience for the wide adoption of artificial pancreas technology in type 1 diabetes. A major challenge in this sense is meal control, with large glycemic impact and yet too burdensome for patients in current hybrid artificial pancreas systems due to carb counting. Consideration of human factors into a system’s design is of paramount importance for a successful technology adoption, since expectations and needs differ from patient to patient. \u00abPerceived usefulness\u00bb and \u00abperceived ease of use\u00bb by the patient yields to its behavioral intention to use the device. Systems designed to admit flexible user interactions at meals, with minimum loss of performance in the absence of meal announcement when compared to current hybrid systems, are needed. Insulin-pramlintide systems are identified as expected major players to achieve this objective.<\/p>\n

The starting hypothesis of this project is that parallel multiple-input control architectures offer the required flexibility to accommodate to different levels of user interaction at meals without detriment of glycemic control, which may involve additional control actions with important constraints due to side effects such as pramlintide, analogously to glucagon. The overall goal of this project is to develop such new postprandial control strategies for an artificial pancreas with flexible user interactions at mealtime to maximize perceived usefulness and ease of use by patients. Clinical evaluation will be performed through mixed meal in-hospital and free-living ambulatory studies to analyze postprandial performance and system usability of developments with most immediate clinical translation. In particular, these studies will challenge the system with announced\/unannounced meals, and meals with different nutritional composition.<\/p>\n

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People<\/h4>\n

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Universitat Polit\u00e9cnica de Val\u00e8ncia<\/h6>\n
    \n
  • Jorge Bondia (coordinador)<\/li>\n
  • Jos\u00e9 Luis D\u00edez<\/li>\n
  • Pedro Garc\u00eda<\/li>\n
  • Sergio Romero<\/li>\n
  • Beatriz Ricarte<\/li>\n
  • Juan Fernando Mart\u00edn (Personal doctor)<\/li>\n
  • Ricardo Sanz (Personal doctor)<\/li>\n
  • Alejandro J. Laguna (Personal doctor)<\/li>\n
  • Iv\u00e1n Sala (Personal doctor)<\/li>\n
  • Clara Furi\u00f3 (Personal doctor)<\/li>\n
  • Mario Mart\u00ednez (Personal investigador de car\u00e1cter predoctoral)<\/li>\n
  • Pablo Rodr\u00edguez-Bobada (Personal investigador de car\u00e1cter predoctoral)<\/li>\n<\/ul>\n

    [\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.16″ custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb][et_pb_text admin_label=\u00bbTexto\u00bb _builder_version=\u00bb4.19.0″ background_size=\u00bbinitial\u00bb background_position=\u00bbtop_left\u00bb background_repeat=\u00bbrepeat\u00bb text_orientation=\u00bbjustified\u00bb use_border_color=\u00bboff\u00bb border_style=\u00bbsolid\u00bb global_colors_info=\u00bb{}\u00bb]<\/p>\n

    Hospital Cl\u00ednico Universitario de Valencia<\/h6>\n
      \n
    • Francisco Javier Ampudia<\/li>\n<\/ul>\n
        <\/ul>\n

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        PROJECTS FLEX-AP BEYOND HYBRID ARTIFICIAL PANCREAS SYSTEMS: RELIEVING CARB COUNTING VIA FLEXIBLE-USER-INTERACTION MULTIPLE-INPUT CONTROL ARCHITECTURES (FLEX-AP)Administrative data Program: Subvenciones 2022 programa Prometeo para grupos de investigaci\u00f3n de excelencia.Project reference: CIPROM\/2021\/012Title: Beyond hybrid artificial pancreas systems: relieving carb counting via flexible-user-interaction multiple-input control architectures (FLEX-AP)Participating centers: Universitat Polit\u00e8cnica de Val\u00e8nciaPrincipal investigator: Jorge BondiaFunded by: Generalitat Valenciana, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-2877","page","type-page","status-publish","hentry"],"yoast_head":"\nFLEX-AP - Tecnodiabetes<\/title>\n<meta name=\"description\" content=\"diabetes, tecnolog\u00eda, investigaci\u00f3n, innovaci\u00f3n, diabetes tipo 1, diabetes tipo 2, p\u00e1ncreas artificial, bomba de insulina, monitor continuo de glucosa, glucosa, insulina, educaci\u00f3n diabetes, simulador diabetes, robot diabetes, CSII, MDI, SAP, CGM, type 1 diabetes, type 2 diabetes, artificial pancreas, insulin pump, continuous glucose monitor, glucose, insulin, diabetes education, diabetes simulator\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/tecnodiabetes.ai2.upv.es\/index.php\/flex-ap\/?lang=en\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"FLEX-AP - 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